Crazy She-Bum

So, flipping through Art Spiegelman's In The Shadow of No Towers, the page that grabbed my attention most is page 6 (possible correlation to my interest in NY Post's infamous gossip page). The reason the page is initially so provoking is the bright alien hell directly on the centerfold. The issues Spiegelman portrays with the antagonist of the panel--the crazy homeless woman with scary eyes and scarier dental hygiene--are penetrating and representative of much more than the surface implications. First of all, I think Spiegelman connects with his readers when he addresses a ubiquitous understanding--that everyone has their neighborhood crazy homeless person, and will certainly notice if he or she is gone or if his or her routine changes. Spiegelman characterizes her as a semi-typical crazy she-bum, but her craziness changes after 9/11. She decides to switch from "hurling antisemitic epithets at me in Russian" to "cursing me in ENGLISH!" He yells back telling her to stop blaming Jews, a point I find very important. Spiegelman might be trying to make a generalization that shirking responsibility in this catastrophe and blaming Jewish people is utterly stupid, even crazy. The panel on the left shows man free-falling out of a tower, with parallel reference to falling out of certainty and into economic disrepair.
I don't know what to make of the very last frame on the panel with mouse and a masked figure--any ideas?